Malarone contains atovaquone and proguanil, which act on different stages of the malaria parasite to prevent its growth and replication.

• Atovaquone disrupts energy production in the malaria parasite
• Proguanil interferes with parasite DNA synthesis
• The combination reduces the risk of resistance and improves effectiveness
• Helps prevent malaria infection or clear uncomplicated malaria when used as treatment

For prevention, consistent daily use is essential before, during, and after travel to malaria-risk areas.

• Active ingredients: Atovaquone & proguanil hydrochloride
• Pharmaceutical form: Film-coated tablets
• Administration route: Oral
• Prescription status: Prescription-only medicine (Rx)

Indications

Malarone is indicated for the prevention of malaria in travellers to endemic regions and for the treatment of uncomplicated malaria caused by Plasmodium falciparum, as determined by a healthcare professional.

Dosage & use

• Dosage depends on body weight, age, and whether it is used for prevention or treatment
• For prevention, dosing typically starts 1–2 days before entering a malaria area, continues during stay, and for several days after leaving
• Tablets should be taken once daily with food or a milky drink to improve absorption
• Complete the full prescribed course, even if you feel well

Warnings

• Not suitable for everyone; inform your prescriber about kidney problems or other medical conditions
• May cause stomach upset, headache, dizziness, or sleep disturbances
• Vomiting shortly after dosing may require medical advice regarding repeat dosing
• Malaria prevention is not 100% effective—use mosquito avoidance measures alongside medication

What is Malarone used for?
Malarone is used to prevent malaria in travellers and to treat uncomplicated malaria when prescribed.

When should I start taking Malarone?
For prevention, Malarone is usually started 1–2 days before travel to a malaria-risk area and continued during the stay and for several days after leaving.

Do I still need mosquito protection?
Yes. Malarone reduces malaria risk but does not replace protective measures such as repellents, bed nets, and protective clothing.

What if I vomit after taking Malarone?
If vomiting occurs shortly after dosing, seek medical advice, as an additional dose may be needed.

Can Malarone be used in children?
Yes, in appropriate strengths and doses based on body weight, as prescribed by a healthcare professional.

Can Malarone be used during pregnancy?
Use during pregnancy or breastfeeding should only occur if clearly advised by a healthcare professional.